A General Hybrid Modeling Framework for Systems Biology Applications: Combining Mechanistic Knowledge with Deep Neural Networks under the SBML Standard

A General Hybrid Modeling Framework for Systems Biology Applications: Combining Mechanistic Knowledge with Deep Neural Networks under the SBML Standard

In this paper, a computational framework is proposed that merges mechanistic modeling with deep neural networks obeying the Systems Biology Markup Language (SBML) standard. Over the last 20 years, the systems biology community has developed a large number of mechanistic models that are currently sto...

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Bibliographic Details
Main Authors: José Pinto, João R. C. Ramos, Rafael S. Costa, Rui Oliveira
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:AI
Subjects:
hybrid modeling
deep neural networks
deep learning
SBML
systems biology
computational modeling
Online Access:https://www.mdpi.com/2673-2688/4/1/14

Internet

https://www.mdpi.com/2673-2688/4/1/14

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