MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

<p>Abstract</p> <p>Background</p> <p>MiR-221 and miR-222 (miR-221/222) are frequently up-regulated in various types of human malignancy including glioblastoma. Recent studies have reported that miR-221/222 regulate cell growth and cell cycle progression by targeting p27...

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Bibliographic Details
Main Authors: Zhang Chun-Zhi, Zhang Jun-Xia, Zhang An-Ling, Shi Zhen-Dong, Han Lei, Jia Zhi-Fan, Yang Wei-Dong, Wang Guang-Xiu, Jiang Tao, You Yong-Ping, Pu Pei-Yu, Cheng Jin-Quan, Kang Chun-Sheng
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/229