Dose-Related Aberrant Inhibition of Intracellular Perforin Expression by S1 Subunit of Spike Glycoprotein That Contains Receptor-Binding Domain from SARS-CoV-2

Studies had shown that severe cases of COVID-19 tend to have high viral loads and correlate with functional impairment of cytotoxic lymphocytes, and the features of cytokine storm syndrome are similar to manifestations of severe influenza that have been partially explained by suppressed perforin exp...

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Bibliographic Details
Main Authors: Chun-Fu Huang, Szu-Min Hsieh, Sung-Ching Pan, Yu-Shang Huang, Shan-Chwen Chang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/9/6/1303