Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter
This study presenting the cryo-EM structure of human SNAPc in complex with U6-1 PSE, significantly enforces our understanding of the mechanism of the SNAPc assembly, the PSE-specific recognition by SNAPc and the PIC assembly on U6 snRNA promoter.
Main Authors: | Jianfeng Sun, Xue Li, Xuben Hou, Sujian Cao, Wenjin Cao, Ye Zhang, Jinyang Song, Manfu Wang, Hao Wang, Xiaodong Yan, Zengpeng Li, Robert G. Roeder, Wei Wang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34639-1 |
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