The Antiarrhythmic Activity of Novel Pyrrolidin-2-one Derivative S-75 in Adrenaline-Induced Arrhythmia

The Antiarrhythmic Activity of Novel Pyrrolidin-2-one Derivative S-75 in Adrenaline-Induced Arrhythmia

Arrhythmia is a quivering or irregular heartbeat that can often lead to blood clots, stroke, heart failure, and other heart-related complications. The limited efficacy and safety of antiarrhythmic drugs require the design of new compounds. Previous research indicated that pyrrolidin-2-one derivative...

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Bibliographic Details
Main Authors: Klaudia Lustyk, Kinga Sałaciak, Paula Zaręba, Agata Siwek, Jacek Sapa, Karolina Pytka
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceuticals
Subjects:
arrhythmia
antiarrhythmic effect
adrenaline-induced arrhythmia
α<sub>1</sub>-adrenoceptor
α<sub>1</sub>-adrenolytics
pyrrolidin-2-one
Online Access:https://www.mdpi.com/1424-8247/14/11/1065

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https://www.mdpi.com/1424-8247/14/11/1065

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