Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.

Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.

The roof plate is a specialized embryonic midline tissue of the central nervous system that functions as a signaling center regulating dorsal neural patterning. In the developing hindbrain, roof plate cells express Gdf7 and previous genetic fate mapping studies showed that these cells contribute mos...

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Bibliographic Details
Main Authors: Frances Y Cheng, Xi Huang, Anuraag Sarangi, Tatiana Ketova, Michael K Cooper, Ying Litingtung, Chin Chiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335071?pdf=render

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http://europepmc.org/articles/PMC3335071?pdf=render

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