RNA-binding proteins potentially regulate the alternative splicing of apoptotic genes during knee osteoarthritis progression

RNA-binding proteins potentially regulate the alternative splicing of apoptotic genes during knee osteoarthritis progression

Abstract Background Alternative splicing (AS) is a principal mode of genetic regulation and one of the most widely used mechanisms to generate structurally and functionally distinct mRNA and protein variants. Dysregulation of AS may result in aberrant transcription and protein products, leading to t...

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Bibliographic Details
Main Authors: Zheng Zhang, Limei Dong, Hai Tao, Yusong Dong, Wei Xiang, Fenghua Tao, Yingchun Zhao
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Genomics
Subjects:
Knee osteoarthritis
RNA binding protein
Alternative splicing
Transcriptome
Differentially expressed genes
Apoptosis
Online Access:https://doi.org/10.1186/s12864-024-10181-w

Internet

https://doi.org/10.1186/s12864-024-10181-w

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