Interaction between Bombyx mori Cytoplasmic Polyhedrosis Virus NSP8 and BmAgo2 Inhibits RNA Interference and Enhances Virus Proliferation

Interaction between Bombyx mori Cytoplasmic Polyhedrosis Virus NSP8 and BmAgo2 Inhibits RNA Interference and Enhances Virus Proliferation

ABSTRACT Some insect viruses encode suppressors of RNA interference (RNAi) to counteract the antiviral RNAi pathway. However, it is unknown whether Bombyx mori cytoplasmic polyhedrosis virus (BmCPV) encodes an RNAi suppressor. In this study, the presence of viral small interfering RNA (vsiRNA) in Bm...

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Bibliographic Details
Main Authors: Jun Pan, Qunnan Qiu, Dhiraj Kumar, Jian Xu, Xinyu Tong, Zeen Shen, Min Zhu, Xiaolong Hu, Chengliang Gong
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Bombyx mori cytoplasmic polyhedrosis virus
nonstructural protein 8
Argonaute 2
suppression of RNAi
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04938-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04938-22

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