Elevated blood and cerebrospinal fluid biomarkers of microglial activation and blood‒brain barrier disruption in anti-NMDA receptor encephalitis

Elevated blood and cerebrospinal fluid biomarkers of microglial activation and blood‒brain barrier disruption in anti-NMDA receptor encephalitis

Abstract Background Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune disease characterized by complex neuropsychiatric syndrome and cerebrospinal fluid (CSF) NMDAR antibodies. Triggering receptor expressed on myeloid cells 2 (TREM2) has been reported to be associated with inflammation of the...

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Bibliographic Details
Main Authors: Haoxiao Chang, Jia Ma, Kai Feng, Ning Feng, Xinxin Wang, Jiali Sun, Tianshu Guo, Yuzhen Wei, Yun Xu, Huabing Wang, Linlin Yin, Xinghu Zhang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Neuroinflammation
Subjects:
Anti-NMDA receptor encephalitis
Microglial activation
Blood‒brain barrier disruption
sTREM2
CD44
MMP9
Online Access:https://doi.org/10.1186/s12974-023-02841-7

Internet

https://doi.org/10.1186/s12974-023-02841-7

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