CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy

CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy

Abstract Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in solid tumors lags significantly behind. Some of the m...

Full description

Bibliographic Details
Main Authors: Kevin Pan, Hizra Farrukh, Veera Chandra Sekhar Reddy Chittepu, Huihong Xu, Chong-xian Pan, Zheng Zhu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Chimeric antigen receptor (CAR)
CAR macrophage
CAR T therapy
CAR NK cells
Adoptive cell transfer
Immunotherapy
Online Access:https://doi.org/10.1186/s13046-022-02327-z

Internet

https://doi.org/10.1186/s13046-022-02327-z

Similar Items