Non-muscle myosin II regulates neuronal actin dynamics by interacting with guanine nucleotide exchange factors.

Non-muscle myosin II (NM II) regulates a wide range of cellular functions, including neuronal differentiation, which requires precise spatio-temporal activation of Rho GTPases. The molecular mechanism underlying the NM II-mediated activation of Rho GTPases is poorly understood. The present study exp...

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Bibliographic Details
Main Authors: Eun-Young Shin, Chan-Soo Lee, Cheong-Yong Yun, So-Yoon Won, Hyong-Kyu Kim, Yong Hee Lee, Sahng-June Kwak, Eung-Gook Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994028?pdf=render