Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore

Abstract Multiple microtubule-directed activities concentrate on mitotic chromosomes to ensure their faithful segregation. These include couplers and dynamics regulators localized at the kinetochore, the microtubule interface built on centromeric chromatin, as well as motor proteins recruited to kin...

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Bibliographic Details
Main Authors: Bram Prevo, Dhanya K. Cheerambathur, William C. Earnshaw, Arshad Desai
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52964-5