Deletion of large-conductance calcium-activated potassium channels promotes vascular remodelling through the CTRP7-mediated PI3K/Akt signaling pathway

Deletion of large-conductance calcium-activated potassium channels promotes vascular remodelling through the CTRP7-mediated PI3K/Akt signaling pathway

The large-conductance calcium-activated potassium (BK) channel is a critical regulator and potential therapeutic target of vascular tone and architecture, and abnormal expression or dysfunction of this channel is linked to many vascular diseases. Vascular remodelling is the early pathological basis...

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Bibliographic Details
Main Authors: Bi Jing, Duan Yanru, Wang Meili, He Chunyu, Li Xiaoyue, Zhang Xi, Tao Yan, Du Yunhui, Liu Huirong
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
large-conductance calcium-activated potassium channel
vascular remodelling
vascular smooth muscle cell
C1q/tumor necrosis factor-related protein 7
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022179

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https://www.sciengine.com/doi/10.3724/abbs.2022179

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