Cancer associated fibroblasts: phenotypic and functional heterogeneity

Cancer associated fibroblasts (CAFs) are the most abundant stromal cell-type in solid tumor-microenvironment (TME) and have emerged as key player in tumor progression. CAFs establish communication with cancer cells through paracrine mechanisms or via direct cell adhesion as well as influence the can...

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Bibliographic Details
Main Authors: Ankit Kumar Patel, Sandeep Singh
Format: Article
Language:English
Published: IMR Press 2020-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/25/5/10.2741/4843