Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

Characterization of tumor-associated reactive astrocytes in gliomas by single-cell and bulk tumor sequencing

ObjectiveAstrocytes constitute approximately 30% of cells in gliomas and play important roles in synapse construction and survival. Recently, JAK/STAT pathway activation associated with a new type of astrocyte was reported. However, the implications of these tumor-associated reactive astrocytes (TAR...

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Bibliographic Details
Main Authors: Chuan-bao Zhang, Zhi-liang Wang, Han-jie Liu, Zheng Wang, Wang Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neurology
Subjects:
reactive astrocytes
glioma
molecular and genomic features
immunotherapy
sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1193844/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1193844/full

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