SERPIN-Derived Small Peptide (SP16) as a Potential Therapeutic Agent against HIV-Induced Inflammatory Molecules and Viral Replication in Cells of the Central Nervous System

SERPIN-Derived Small Peptide (SP16) as a Potential Therapeutic Agent against HIV-Induced Inflammatory Molecules and Viral Replication in Cells of the Central Nervous System

Despite the success of combined antiretroviral therapy (cART) increasing the survival rate in human immunodeficiency virus (HIV) patients, low levels of viremia persist in the brain of patients leading to glia (microglia and astrocytes)-induced neuroinflammation and consequently, the reactivation of...

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Bibliographic Details
Main Authors: Yemmy Soler, Myosotys Rodriguez, Dana Austin, Cyrille Gineste, Cohava Gelber, Nazira El-Hage
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
serine protease inhibitors
blood-brain barrier
low-density lipoprotein receptor related-protein 1
therapeutic efficacy
intranasal delivery
Online Access:https://www.mdpi.com/2073-4409/12/4/632

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https://www.mdpi.com/2073-4409/12/4/632

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