Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway

Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway

Pulmonary ischemia/reperfusion (IR) injury is the leading cause of acute lung injury, which is mainly attributed to reactive oxygen species (ROS) induced cell injuries and apoptosis. Since rosmarinic acid (RA) has been identified as an antioxidant natural ester, this natural compound might protect a...

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Bibliographic Details
Main Authors: Wenbin Luo, Yu Tao, Shengnan Chen, Hao Luo, Xiaoping Li, Shuang Qu, Ken Chen, Chunyu Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
rosmarinic acid
pulmonary ischemia/reperfusion injury
oxidative stress
apoptosis
PI3K/AKT
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.860944/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.860944/full

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