Identification of microsatellite instability and immune-related prognostic biomarkers in colon adenocarcinoma

Identification of microsatellite instability and immune-related prognostic biomarkers in colon adenocarcinoma

BackgroundColon adenocarcinoma (COAD) is a prevalent malignancy that causes significant mortality. Microsatellite instability plays a pivotal function in COAD development and immunotherapy resistance. However, the detailed underlying mechanism requires further investigation. Consequently, identifyin...

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Bibliographic Details
Main Authors: Ziquan Sun, Guodong Li, Desi Shang, Jinning Zhang, Lianjie Ai, Ming Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
colon adenocarcinoma (COAD)
microsatellite instability (MSI)
immune microenvironment
prognostic biomarkers
drug response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.988303/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.988303/full

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