No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

ABSTRACT Sputum collection and testing for tuberculosis (TB) have been problematic due to the potential for aerosolization, difficulty in generating a quality sample, and complex DNA extraction methods. Tongue swabs are inexpensive, minimally invasive, and a promising alternative to sputum collectio...

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Bibliografske podrobnosti
Main Authors: Charlotte L. Ahls, Duncan Emsweller, Seth J. Helfers, Xin Niu, Douglas Wilson, Leah R. Padgett, Paul K. Drain
Format: Article
Jezik:English
Izdano: American Society for Microbiology 2024-01-01
Serija:Microbiology Spectrum
Teme:
Online dostop:https://journals.asm.org/doi/10.1128/spectrum.03107-23