No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

ABSTRACT Sputum collection and testing for tuberculosis (TB) have been problematic due to the potential for aerosolization, difficulty in generating a quality sample, and complex DNA extraction methods. Tongue swabs are inexpensive, minimally invasive, and a promising alternative to sputum collectio...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Charlotte L. Ahls, Duncan Emsweller, Seth J. Helfers, Xin Niu, Douglas Wilson, Leah R. Padgett, Paul K. Drain
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: American Society for Microbiology 2024-01-01
Cyfres:Microbiology Spectrum
Pynciau:
Mycobacterium tuberculosis
tongue swab
qPCR
direct lysis
Mynediad Ar-lein:https://journals.asm.org/doi/10.1128/spectrum.03107-23

Rhyngrwyd

https://journals.asm.org/doi/10.1128/spectrum.03107-23

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