No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

ABSTRACT Sputum collection and testing for tuberculosis (TB) have been problematic due to the potential for aerosolization, difficulty in generating a quality sample, and complex DNA extraction methods. Tongue swabs are inexpensive, minimally invasive, and a promising alternative to sputum collectio...

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Bibliografiska uppgifter
Huvudupphovsmän: Charlotte L. Ahls, Duncan Emsweller, Seth J. Helfers, Xin Niu, Douglas Wilson, Leah R. Padgett, Paul K. Drain
Materialtyp: Artikel
Språk:English
Publicerad: American Society for Microbiology 2024-01-01
Serie:Microbiology Spectrum
Ämnen:
Mycobacterium tuberculosis
tongue swab
qPCR
direct lysis
Länkar:https://journals.asm.org/doi/10.1128/spectrum.03107-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03107-23

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