No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

ABSTRACT Sputum collection and testing for tuberculosis (TB) have been problematic due to the potential for aerosolization, difficulty in generating a quality sample, and complex DNA extraction methods. Tongue swabs are inexpensive, minimally invasive, and a promising alternative to sputum collectio...

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Main Authors: Charlotte L. Ahls, Duncan Emsweller, Seth J. Helfers, Xin Niu, Douglas Wilson, Leah R. Padgett, Paul K. Drain
格式: 文件
语言:English
出版: American Society for Microbiology 2024-01-01
丛编:Microbiology Spectrum
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在线阅读:https://journals.asm.org/doi/10.1128/spectrum.03107-23