LRRC46 Accumulates at the Midpiece of Sperm Flagella and Is Essential for Spermiogenesis and Male Fertility in Mouse

LRRC46 Accumulates at the Midpiece of Sperm Flagella and Is Essential for Spermiogenesis and Male Fertility in Mouse

The sperm flagellum is essential for male fertility. Multiple morphological abnormalities of the sperm flagella (MMAF) is a severe form of asthenoteratozoospermia. MMAF phenotypes are understood to result from pathogenic variants of genes from multiple families including AKAP, DANI, DNAH, RSPH, CCDC...

Full description

Bibliographic Details
Main Authors: Yingying Yin, Wenyu Mu, Xiaochen Yu, Ziqi Wang, Ke Xu, Xinyue Wu, Yuling Cai, Mingyu Zhang, Gang Lu, Wai-Yee Chan, Jinlong Ma, Tao Huang, Hongbin Liu
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
multiple morphological abnormalities of the sperm flagella (MMAF)
leucine rich repeat containing 46 (LRRC46)
male infertility
Online Access:https://www.mdpi.com/1422-0067/23/15/8525

Internet

https://www.mdpi.com/1422-0067/23/15/8525

Similar Items