Androgen‐repressed lncRNA LINC01126 drives castration‐resistant prostate cancer by regulating the switch between O‐GlcNAcylation and phosphorylation of androgen receptor

Androgen‐repressed lncRNA LINC01126 drives castration‐resistant prostate cancer by regulating the switch between O‐GlcNAcylation and phosphorylation of androgen receptor

Abstract Background Prostate cancer (PCa) initially shows satisfactory response to therapies targeting the androgen receptor (AR). However, progression to a castration‐resistant stage indicates poor prognosis in PCa patients. AR signalling still plays a central role in most castration‐resistant pros...

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Bibliographic Details
Main Authors: Yi Cai, Minfeng Chen, Yuchen Gong, Guyu Tang, Zhiwei Shu, Jiaxian Chen, Hengfeng Zhou, Yao He, Zhi Long, Yu Gan
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Clinical and Translational Medicine
Subjects:
androgen receptor
castration‐resistant prostate cancer
long non‐coding RNA
post‐translational modifications
Online Access:https://doi.org/10.1002/ctm2.1531

Internet

https://doi.org/10.1002/ctm2.1531

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