Roles of oxidative stress/JNK/ERK signals in paraquat-triggered hepatic apoptosis

Roles of oxidative stress/JNK/ERK signals in paraquat-triggered hepatic apoptosis

Paraquat (PQ), a toxic and nonselective bipyridyl herbicide, is one of the most extensively used pesticides in agricultural countries. In addition to pneumotoxicity, the liver is an important target organ for PQ poisoning in humans. However, the mechanism of PQ in hepatotoxicity remains unclear. In...

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Bibliographic Details
Main Authors: Kuan-I Lee, Kai-Min Fang, Chun-Ying Kuo, Chun-Fa Huang, Shing-Hwa Liu, Jui-Ming Liu, Wei-Cheng Lai, Kai-Chih Chang, Chin-Chuan Su, Ya-Wen Chen
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Toxicology
Subjects:
Paraquat
Hepatotoxicity
Apoptosis
Oxidative stress
JNK
ERK1/2
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X24000082

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http://www.sciencedirect.com/science/article/pii/S2666027X24000082

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