Homozygous lethality and heterozygous spotting due to a novel missense mutation in the mouse Kit gene
N-ethyl-N-nitrosourea (ENU) mutagenesis in mice can be used to study gene function in vivo and to establish genetic mouse models of human disease. In this study, a white spotted mouse (named KitW-1Bao) was obtained by ENU-induced mutagenesis. Inheritance testing showed a single-gene dominant mutatio...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2009-12-01
|
| Series: | Current Zoology |
| Subjects: | |
| Online Access: | http://www.currentzoology.org/paperdetail.asp?id=11328 |