Mokko Lactone Alleviates Doxorubicin-Induced Cardiotoxicity in Rats via Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities

Mokko Lactone Alleviates Doxorubicin-Induced Cardiotoxicity in Rats via Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities

Doxorubicin (DOX), a commonly utilized anthracycline antibiotic, suffers deleterious side effects such as cardiotoxicity. Mokko lactone (ML) is a naturally occurring guainolide sesquiterpene with established antioxidant and anti-inflammatory actions. This study aimed at investigating the protective...

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Bibliographic Details
Main Authors: Alaa Sirwi, Rasheed A. Shaik, Abdulmohsin J. Alamoudi, Basma G. Eid, Mahmoud A. Elfaky, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Hossam M. Abdallah, Ashraf B. Abdel-Naim
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Nutrients
Subjects:
doxorubicin
mokko lactone
heart
Online Access:https://www.mdpi.com/2072-6643/14/4/733

Internet

https://www.mdpi.com/2072-6643/14/4/733

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