Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort

Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort

Abstract Background Recent studies show that human gut microbial composition can determine whether a patient is a responder or non-responder to immunotherapy but have not identified a common microbial signal shared by responding patients. The functional relationship between immunity, intestinal micr...

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Bibliographic Details
Main Authors: Rachel C. Newsome, Raad Z. Gharaibeh, Christine M. Pierce, Wildson Vieira da Silva, Shirlene Paul, Stephanie R. Hogue, Qin Yu, Scott Antonia, Jose R. Conejo-Garcia, Lary A. Robinson, Christian Jobin
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Genome Medicine
Subjects:
Microbiome
Immunotherapy
Non-small cell lung cancer
Fecal microbiota transplant
Online Access:https://doi.org/10.1186/s13073-022-01037-7

Internet

https://doi.org/10.1186/s13073-022-01037-7

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