Microwave-Mediated, Catalyst-Free Synthesis of 1,2,4-Triazolo[1,5-<i>a</i>]pyridines from Enaminonitriles

Microwave-Mediated, Catalyst-Free Synthesis of 1,2,4-Triazolo[1,5-<i>a</i>]pyridines from Enaminonitriles

A catalyst-free, additive-free, and eco-friendly method for synthesizing 1,2,4-triazolo[1,5-<i>a</i>]pyridines under microwave conditions has been established. This tandem reaction involves the use of enaminonitriles and benzohydrazides, a transamidation mechanism followed by nucleophili...

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Bibliographic Details
Main Authors: Kwanghee Lee, Young-Ah Kim, Chanhyun Jung, Jaeuk Sim, Shanmugam Rajasekar, Jae-Hwan Kwak, Mayavan Viji, Jae-Kyung Jung
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
enaminonitrile
1,2,4-triazolo[1,5-<i>a</i>]pyridine
microwave irradiation
tandem reaction
acyl hydrazide
Online Access:https://www.mdpi.com/1420-3049/29/4/894

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https://www.mdpi.com/1420-3049/29/4/894

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