Epithelial-mesenchymal transition, regulated by β-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis.

Eosinophilic Esophagitis (EoE) is an antigen-triggered inflammatory condition of the esophageal lining characterized by eosinophilic infiltration. EoE is associated with significant remodeling, and although this remodeling is reversed by current treatment regimens, symptoms of EoE and associated rem...

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Bibliographic Details
Main Authors: Elizabeth Garcia, Zeenat Ladak, Takaaki Landry, Michael Wollin, Amit R L Persad, Consolato M Sergi, Hien Q Huynh, Rabindranath Persad, Sujata Persad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0264622