Ligand-based pharmacophore modelling in search of novel anaplastic lymphoma kinase inhibitors
Non-small-cell lung cancer (NSCLC) accounts for 85 % of lung cancer cases and is the leading cause of mortality globally. Anaplastic lymphoma kinase (ALK) has been identified as an NSCLC mutational cancer mediator. Many additional ALK inhibitors are currently undergoing clinical studies. Many ALK in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622004714 |