Identification and functional validation of SRC and RAPGEF1 as new direct targets of miR-203, involved in regulation of epidermal homeostasis

Abstract The epidermis is mostly composed of keratinocytes and forms a protecting barrier against external aggressions and dehydration. Epidermal homeostasis is maintained by a fine-tuned balance between keratinocyte proliferation and differentiation. In the regulation of this process, the keratinoc...

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Bibliographic Details
Main Authors: Christelle Golebiewski, Cécile Gastaldi, Diane-Lore Vieu, Bernard Mari, Roger Rezzonico, Françoise Bernerd, Claire Marionnet
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40441-w