From Boolean Network Model to Continuous Model Helps in Design of Functional Circuits.

Computational circuit design with desired functions in a living cell is a challenging task in synthetic biology. To achieve this task, numerous methods that either focus on small scale networks or use evolutionary algorithms have been developed. Here, we propose a two-step approach to facilitate the...

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Bibliographic Details
Main Authors: Bin Shao, Xiang Liu, Dongliang Zhang, Jiayi Wu, Qi Ouyang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4464762?pdf=render