Identification of disease causing loci using an array-based genotyping approach on pooled DNA

<p>Abstract</p> <p>Background</p> <p>Pooling genomic DNA samples within clinical classes of disease followed by genotyping on whole-genome SNP microarrays, allows for rapid and inexpensive genome-wide association studies. Key to the success of these studies is the accur...

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Bibliographic Details
Main Authors: Puffenberger Erik G, Lee Anne M, Kruer Michael C, Zismann Victoria L, Hu-Lince Diane, Huentelman Matthew J, Craig David W, Pearson John M, Stephan Dietrich A
Format: Article
Language:English
Published: BMC 2005-09-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/138