hFcγRIIa: a double-edged sword in osteoclastogenesis and bone balance in transgenic mice

Rheumatoid arthritis (RA) is a chronic autoimmune disease accompanied by local and systemic bone loss. FcγRs, especially FcγRIIa (hFcγRIIa), have been implicated in the pathogenesis of RA. However, the contribution of hFcγRIIa to bone loss has not been fully elucidated. In the present study, we demo...

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Bibliographic Details
Main Authors: Jie Miao, Hong-Min Wang, Xiao-Hua Pan, Zheng Gong, Xiao-Ming Gao, Fang-Yuan Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1425670/full