Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis
Phosphopantetheinyl transferases (PPTases) are key elements in the modular syntheses performed by multienzyme systems such as polyketide synthases. PPTases transfer phosphopantetheine derivatives from Coenzyme A to carrier proteins (CPs), thus orchestrating substrate supply. We describe an efficient...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-12-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.12140 |