ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination.

ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination.

The ESX systems from Mycobacterium tuberculosis are responsible for the secretion of highly immunogenic proteins of key importance for bacterial survival and growth. The two prototypic proteins, ESAT-6 (EsxA from ESX-1) and TB10.4 (EsxH from ESX-3) share a lot of characteristics regarding genome org...

Full description

Bibliographic Details
Main Authors: Truc Hoang, Claus Aagaard, Jes Dietrich, Joseph P Cassidy, Gregory Dolganov, Gary K Schoolnik, Carina Vingsbo Lundberg, Else Marie Agger, Peter Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861245?pdf=render

Internet

http://europepmc.org/articles/PMC3861245?pdf=render

Similar Items