Modulating hierarchical self-assembly in thermoresponsive intrinsically disordered proteins through high-temperature incubation time

Abstract The cornerstone of structural biology is the unique relationship between protein sequence and the 3D structure at equilibrium. Although intrinsically disordered proteins (IDPs) do not fold into a specific 3D structure, breaking this paradigm, some IDPs exhibit large-scale organization, such...

Full description

Bibliographic Details
Main Authors: Vaishali Sethi, Dana Cohen-Gerassi, Sagi Meir, Max Ney, Yulia Shmidov, Gil Koren, Lihi Adler-Abramovich, Ashutosh Chilkoti, Roy Beck
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48483-w