Loss of endogenous Nox2-NADPH oxidase does not prevent age-induced platelet activation and arterial thrombosis in mice

Background: Reactive oxygen species are known to contribute to platelet hyperactivation and thrombosis during aging; however, the mechanistic contribution of the specific oxidative pathway remains elusive. Objectives: We hypothesized that during aging, endogenous Nox2-NADPH oxidase contributes to pl...

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Bibliografiska uppgifter
Huvudupphovsmän: Azaj Ahmed, Gokul Patil, Vijay K. Sonkar, Melissa Jensen, Jennifer Streeter, Sanjana Dayal
Materialtyp: Artikel
Språk:English
Publicerad: Elsevier 2024-10-01
Serie:Research and Practice in Thrombosis and Haemostasis
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Länkar:http://www.sciencedirect.com/science/article/pii/S2475037924002929