Adolescent nicotine exposure promotes adulthood opioid consumption that persists despite adverse consequences and increases the density of insular perineuronal nets

Adolescence marks a sensitive period for neurodevelopment wherein exposure to drugs of abuse may disrupt maturation and induce persistent changes in neurophysiology which may exacerbate the risk for developing substance use disorders in adulthood. Adolescent nicotine exposure (ANE) enhances motivati...

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Bibliographic Details
Main Authors: S.C. Honeycutt, A. Mukherjee, M.S. Paladino, E.A. Gilles-Thomas, G.C. Loney
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Addiction Neuroscience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772392524000099