Colon-Targeted eNAMPT-Specific Peptide Systems for Treatment of DSS-Induced Acute and Chronic Colitis in Mouse

Nicotinamide phosphoribosyl transferase (NAMPT) is required to maintain the NAD<sup>+</sup> pool, among which extracellular (e) NAMPT is associated with inflammation, mainly mediated by macrophages. However, the role of (e) NAMPT in inflammatory macrophages in ulcerative colitis is insuf...

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Bibliographic Details
Main Authors: Jae-Sung Kim, Hyo Keun Kim, Minsoo Kim, Sein Jang, Euni Cho, Seok-Jun Mun, Joongho Lee, Dawon Hong, Seokhyun Yoon, Chul-Su Yang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/12/2376