Structure-Guided Strategies of Targeted Therapies for Patients with <i>EGFR</i>-Mutant Non–Small Cell Lung Cancer

Structure-Guided Strategies of Targeted Therapies for Patients with <i>EGFR</i>-Mutant Non–Small Cell Lung Cancer

Oncogenic mutations within the EGFR kinase domain are well-established driver mutations in non–small cell lung cancer (NSCLC). Small-molecule tyrosine kinase inhibitors (TKIs) specifically targeting these mutations have improved treatment outcomes for patients with this subtype of NSCLC. The selecti...

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Bibliographic Details
Main Authors: Zhenfang Du, Jinghan Sun, Yunkai Zhang, Nigaerayi Hesilaiti, Qi Xia, Heqing Cui, Na Fan, Xiaofang Xu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomolecules
Subjects:
non–small cell lung cancer
EGFR
structure
targeted therapy
Online Access:https://www.mdpi.com/2218-273X/13/2/210

Internet

https://www.mdpi.com/2218-273X/13/2/210

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