Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells

Cysteine cathepsins are lysosomal peptidases involved at different levels in the processes of the innate and adaptive immune responses. Some, such as cathepsins B, L and H are expressed constitutively in most immune cells. In cells of innate immunity they play a role in cell adhesion and phagocytosi...

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Bibliographic Details
Main Authors: Janko eKos, Milica ePerišić Nanut, Jerica eSabotič, Anahit eJewett
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00616/full