Targeting FMN, TPP, SAM-I, and glmS Riboswitches with Chimeric Antisense Oligonucleotides for Completely Rational Antibacterial Drug Development

Antimicrobial drug resistance has emerged as a significant challenge in contemporary medicine due to the proliferation of numerous bacterial strains resistant to all existing antibiotics. Meanwhile, riboswitches have emerged as promising targets for discovering antibacterial drugs. Riboswitches are...

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Bibliographic Details
Main Authors: Nikolet Pavlova, Martina Traykovska, Robert Penchovsky
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/12/11/1607