Leucine Supplementation Prevents the Development of Skeletal Muscle Dysfunction in a Rat Model of HFpEF

Leucine Supplementation Prevents the Development of Skeletal Muscle Dysfunction in a Rat Model of HFpEF

Heart failure with preserved ejection fraction (HFpEF) is associated with exercise intolerance due to alterations in the skeletal muscle (SKM). Leucine supplementation is known to alter the anabolic/catabolic balance and to improve mitochondrial function. Thus, we investigated the effect of leucine...

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Bibliographic Details
Main Authors: Paula Ketilly Nascimento Alves, Antje Schauer, Antje Augstein, Maria-Elisa Prieto Jarabo, Anita Männel, Peggy Barthel, Beatrice Vahle, Anselmo S. Moriscot, Axel Linke, Volker Adams
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
HFpEF
ZSF1
leucine
mitochondria
diastolic dysfunction
skeletal muscle dysfunction
Online Access:https://www.mdpi.com/2073-4409/13/6/502

Internet

https://www.mdpi.com/2073-4409/13/6/502

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