Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D

Abstract Background Three-dimensional cultures of mammary epithelial cells allow for biologically-relevant studies of the development of the mammary gland in rodents and humans under normal and pathological conditions, like carcinogenesis. Under these conditions, mammotropic hormones play significan...

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Bibliographic Details
Main Authors: Michael F. Sweeney, Carlos Sonnenschein, Ana M. Soto
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-018-0534-y