Comparison of analysis methods and design choices for treatment-by-period interaction in unidirectional switch designs: a simulation study

Abstract Background Due to identifiability problems, statistical inference about treatment-by-period interactions has not been discussed for stepped wedge designs in the literature thus far. Unidirectional switch designs (USDs) generalize the stepped wedge designs and allow for estimation and testin...

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Bibliographic Details
Main Authors: Zhuozhao Zhan, Geertruida H. de Bock, Edwin R. van den Heuvel
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-022-01765-9