A dysbiotic gut microbiome suppresses antibody mediated-protection against Vibrio cholerae

Summary: Cholera is a severe diarrheal disease that places a significant burden on global health. Cholera’s high morbidity demands effective prophylactic strategies, but oral cholera vaccines exhibit variable efficacy in human populations. One contributor of variance in human populations is the gut...

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Bibliographic Details
Main Authors: John C. Macbeth, Rui Liu, Salma Alavi, Ansel Hsiao
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221014140