HLA-B*57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B*57:01-negative subjects
Abstract Background The presence of the HLA-B*57:01 allele in HIV-infected subjects is associated with a higher risk of abacavir-associated hypersensitivity reaction (ABC HSR). HLA-B*57:01 allele prevalence varies in different populations, but HLA-B*57:01 testing with immunological confirmation has...
Autori principali: | , , , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
BMC
2017-04-01
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Serie: | BMC Infectious Diseases |
Soggetti: | |
Accesso online: | http://link.springer.com/article/10.1186/s12879-017-2331-y |