Combined treatment of disulfiram with PARP inhibitors suppresses ovarian cancer

Combined treatment of disulfiram with PARP inhibitors suppresses ovarian cancer

IntroductionDue to the difficulty of early diagnosis, nearly 70% of ovarian cancer patients are first diagnosed at an advanced stage. Thus, improving current treatment strategies is of great significance for ovarian cancer patients. Fast-developing poly (ADP-ribose) polymerases inhibitors (PARPis) h...

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Bibliographic Details
Main Authors: Bin Tang, Min Wu, Lin Zhang, Shuyi Jian, Shiyi Lv, Tongyuan Lin, Shuangshuang Zhu, Layang Liu, Yixue Wang, Zhengfang Yi, Feiyun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Oncology
Subjects:
poly (ADP-ribose) polymerase inhibitors
ovarian cancer
drug combination
disulfiram
DNA damage repair
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1154073/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1154073/full

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